Dome over a tomb in a side chapel in the Cathedral of Santo Domingo in the Dominican Republic. The Capilla de Santa Ana contains the tomb of Bishop Rodrigo de Bastidas, d. 1570. The Cathedral of Santa Maria La Menor, or Saint Mary of the Incarnation, was the first cathedral built in the Americas, completed about 1540 A.D. It is a Minor Basilica and is located in the old Colonial City of Santo Domingo, Dominican Republic. A UNESCO World Heritage Site.